Protein Arginine Methyltransferase 5 Inhibition Upregulates Foxp3(+) Regulatory T Cells Frequency and Function during the Ulcerative Colitis

Ulcerative colitis (UC) pathogenesis is related to imbalance of immune responses, and the equilibrium between inflammatory T cells and Foxp3(+) regulatory T cells (Tregs) plays an important role in the intestinal homeostasis. Protein arginine methyltransferases (PRMTs) regulate chromatin remodeling...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zheng, Yingxia, Huang, Liya, Ge, Wensong, Yang, Ming, Ma, Yanhui, Xie, Guohua, Wang, Weiwei, Bian, Bingxian, Li, Li, Nie, Hong, Shen, Lisong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440547/
https://ncbi.nlm.nih.gov/pubmed/28588584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00596
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