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Endothelial-specific expression of caveolin-1 impairs microvascular permeability and angiogenesis

The functions of caveolae and/or caveolins in intact animals are beginning to be explored. Here, by using endothelial cell-specific transgenesis of the caveolin-1 (Cav-1) gene in mice, we show the critical role of Cav-1 in several postnatal vascular paradigms. First, increasing levels of Cav-1 do no...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Bauer, Philip M., Yu, Jun, Chen, Yan, Hickey, Reed, Bernatchez, Pascal N., Looft-Wilson, Robin, Huang, Yan, Giordano, Frank, Stan, Radu V., Sessa, William C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544041/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15615855/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0406092102
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