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Tamoxifen for induction of Cre-recombination may confound fibrosis studies in female mice

A variety of conditional knock-out mice relying on Tamoxifen-driven ERT2/Cre -mediated recombination are available and have been used to study involvement of specific genes in kidney disease. However, recent data suggest that Tamoxifen itself might attenuate fibrosis when administered during experim...

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Detalles Bibliográficos
Publicado en:J Cell Commun Signal
Main Authors: Falke, Lucas L., Broekhuizen, Roel, Huitema, Alwin, Maarseveen, Erik, Nguyen, Tri Q., Goldschmeding, Roel
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440352/
https://ncbi.nlm.nih.gov/pubmed/28497232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-017-0390-x
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