Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance

Macrophages are critical effectors of bacterial clearance and must retain viability, despite exposure to toxic bacterial products, until key antimicrobial functions are performed. Subsequently, host-mediated macrophage apoptosis aids resolution of infection. The ability of macrophages to make this t...

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Detalhes bibliográficos
Principais autores: Marriott, Helen M., Bingle, Colin D., Read, Robert C., Braley, Karen E., Kroemer, Guido, Hellewell, Paul G., Craig, Ruth W., Whyte, Moira K.B., Dockrell, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544034/
https://ncbi.nlm.nih.gov/pubmed/15650769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200521766
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