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Mechanistic and Biological Considerations of Oxidatively Damaged DNA for Helicase-dependent Pathways of Nucleic Acid Metabolism

Cells are under constant assault from reactive oxygen species that occur endogenously or arise from environmental agents. An important consequence of such stress is the generation of oxidatively damaged DNA, which is represented by a wide range of non-helix distorting and helix-distorting bulkier le...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Crouch, Jack D., Brosh, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440220/
https://ncbi.nlm.nih.gov/pubmed/27884703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.11.022
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