Autophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer

Epidermal growth factor receptor (EGFR) is over-expressed in about 50% of Triple negative breast cancers (TNBCs), but EGFR inhibitors have not been effective in treating TNBC patients. Increasing evidence supports that autophagy was related to drug resistance at present. However, the role and the me...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Liu, Zhaoyun, He, Kewen, Ma, Qinghua, Yu, Qian, Liu, Chenyu, Ndege, Isabella, Wang, Xinzhao, Yu, Zhiyong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439698/
https://ncbi.nlm.nih.gov/pubmed/28531218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177694
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker