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Autophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer

Epidermal growth factor receptor (EGFR) is over-expressed in about 50% of Triple negative breast cancers (TNBCs), but EGFR inhibitors have not been effective in treating TNBC patients. Increasing evidence supports that autophagy was related to drug resistance at present. However, the role and the me...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Liu, Zhaoyun, He, Kewen, Ma, Qinghua, Yu, Qian, Liu, Chenyu, Ndege, Isabella, Wang, Xinzhao, Yu, Zhiyong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439698/
https://ncbi.nlm.nih.gov/pubmed/28531218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177694
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