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Fasting Increases the In Vivo Gene Delivery of AAV Vectors

Successful gene therapy of many genetic diseases requires efficient delivery of the gene to several tissues of the organism. Adeno‐associated virus (AAV) is, to date, the sole vehicle that allows to achieving this result but only at the condition of administering very large amounts of vectors. This,...

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Dettagli Bibliografici
Pubblicato in:Clin Transl Sci
Autori principali: Moulay, Gilles, Scherman, Daniel, Kichler, Antoine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Inc 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439638/
https://ncbi.nlm.nih.gov/pubmed/21207763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2010.00245.x
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