Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model

BACKGROUND. To expedite the evaluation of vaccines against paratyphoid fever, we aimed to develop the first human challenge model of Salmonella enterica serovar Paratyphi A infection. METHODS. Two groups of 20 participants underwent oral challenge with S. Paratyphi A following sodium bicarbonate pre...

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Publicat a:Clin Infect Dis
Autors principals: Dobinson, Hazel C., Gibani, Malick M., Jones, Claire, Thomaides-Brears, Helena B., Voysey, Merryn, Darton, Thomas C., Waddington, Claire S., Campbell, Danielle, Milligan, Iain, Zhou, Liqing, Shrestha, Sonu, Kerridge, Simon A., Peters, Anna, Stevens, Zoe, Podda, Audino, Martin, Laura B., D’Alessio, Flavia, Thanh, Duy Pham, Basnyat, Buddha, Baker, Stephen, Angus, Brian, Levine, Myron M., Blohmke, Christoph J., Pollard, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Major Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439345/
https://ncbi.nlm.nih.gov/pubmed/28158395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cix042
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