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Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model

BACKGROUND. To expedite the evaluation of vaccines against paratyphoid fever, we aimed to develop the first human challenge model of Salmonella enterica serovar Paratyphi A infection. METHODS. Two groups of 20 participants underwent oral challenge with S. Paratyphi A following sodium bicarbonate pre...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Dobinson, Hazel C., Gibani, Malick M., Jones, Claire, Thomaides-Brears, Helena B., Voysey, Merryn, Darton, Thomas C., Waddington, Claire S., Campbell, Danielle, Milligan, Iain, Zhou, Liqing, Shrestha, Sonu, Kerridge, Simon A., Peters, Anna, Stevens, Zoe, Podda, Audino, Martin, Laura B., D’Alessio, Flavia, Thanh, Duy Pham, Basnyat, Buddha, Baker, Stephen, Angus, Brian, Levine, Myron M., Blohmke, Christoph J., Pollard, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439345/
https://ncbi.nlm.nih.gov/pubmed/28158395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cix042
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