AIM2 Inflammasome Is Critical for Influenza-Induced Lung Injury and Mortality

The absent in melanoma 2 (AIM2) inflammasome plays an important role in many viral and bacterial infections, but very little is known about its role in RNA virus infection, including influenza A virus (IAV). In this study, we have designed in vivo and in vitro studies to determine the role of AIM2 i...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Zhang, Hongbo, Luo, Jiadi, Alcorn, John F., Chen, Kong, Fan, Songqing, Pilewski, Joseph, Liu, Aizhong, Chen, Wei, Kolls, Jay K., Wang, Jieru
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2017
Assuntos:
Infectious Disease and Host Response
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439025/
https://ncbi.nlm.nih.gov/pubmed/28424239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600714
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