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Increased Mortality from Influenza Infection in Long-chain Acyl-CoA Dehydrogenase Knockout Mice

We previously showed that the mitochondrial fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase (LCAD) is expressed in alveolar type II pneumocytes and that LCAD-/- mice have altered breathing mechanics and surfactant defects. Here, we hypothesized that LCAD-/-mice would be susceptible to...

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Dades bibliogràfiques
Publicat a:Biochem Biophys Res Commun
Autors principals: Shinde, Apurva, Luo, Jiadi, Bharathi, Sivakama S., Shi, Huifang, Beck, Megan E., McHugh, Kevin J., Alcorn, John F., Wang, Jieru, Goetzman, Eric S.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850965/
https://ncbi.nlm.nih.gov/pubmed/29458021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.02.135
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