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Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases

In 2002, intracellular protein complexes known as the inflammasomes were discovered and were shown to have a crucial role in the sensing of intracellular pathogen- and danger-associated molecular patterns (PAMPs and DAMPs). Activation of the inflammasomes results in the processing and subsequent sec...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Fenini, Gabriele, Contassot, Emmanuel, French, Lars E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438978/
https://ncbi.nlm.nih.gov/pubmed/28588486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00278
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