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Blocking antibodies induced by immunization with a hypoallergenic parvalbumin mutant reduce allergic symptoms in a mouse model of fish allergy
BACKGROUND: Fish is a frequent elicitor of severe IgE-mediated allergic reactions. Beside avoidance, there is currently no allergen-specific therapy available. Hypoallergenic variants of the major fish allergen, parvalbumin, for specific immunotherapy based on mutation of the 2 calcium-binding sites...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | J Allergy Clin Immunol |
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Κύριοι συγγραφείς: | , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2016
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5438872/ https://ncbi.nlm.nih.gov/pubmed/27876628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.10.018 |
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