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IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway
PURPOSE: Numerous studies have reported that glioma patients with isocitrate dehydrogenase 1(IDH1) R132H mutation are sensitive to temozolomide treatment. However, the mechanism of IDH1 mutations on the chemosensitivity of glioma remains unclear. In this study, we investigated the role and the poten...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5438698/ https://ncbi.nlm.nih.gov/pubmed/28427200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15868 |
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