miR-219-5p targets CaMKIIγ to attenuate morphine tolerance in rats

Morphine tolerance is a clinical challenge in pain management. Emerging evidence suggests that microRNA (miRNA) plays a regulatory role in the development of morphine tolerance. miR-219-5p (miR-219) targets calmodulin-dependent protein kinase II γ (CaMKIIγ) to activate central pain sensitization via...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Wang, Jian, Xu, Wei, Shao, Jiali, He, Zhenghua, Ding, Zhuofeng, Huang, Jiangju, Guo, Qulian, Zou, Wangyuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438643/
https://ncbi.nlm.nih.gov/pubmed/28423675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15997
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