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EndophilinAs regulate endosomal sorting of BDNF-TrkB to mediate survival signaling in hippocampal neurons

The sorting of activated receptors into distinct endosomal compartments is essential to activate specific signaling cascades and cellular events including growth and survival. However, the proteins involved in this sorting are not well understood. We discovered a novel role of EndophilinAs in sortin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Burk, Katja, Murdoch, John D., Freytag, Siona, Koenig, Melanie, Bharat, Vinita, Markworth, Ronja, Burkhardt, Susanne, Fischer, Andre, Dean, Camin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438371/
https://ncbi.nlm.nih.gov/pubmed/28526875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02202-4
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