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Chitosan-Dextran sulfate coated doxorubicin loaded PLGA-PVA-nanoparticles caused apoptosis in doxorubicin resistance breast cancer cells through induction of DNA damage

To overcome the toxicity, pharmacokinetics and drug resistance associated with doxorubicin (DOX), a strategy was developed by encapsulating DOX- loaded-PLGA-PVA- nanoparticles within chitosan-dextran sulfate nanoparticles (CS-DS) [CS-DS-coated-DOX-loaded -PLGA-PVA-NP] and study the sensitivity again...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Siddharth, Sumit, Nayak, Anmada, Nayak, Deepika, Bindhani, Birendra Kumar, Kundu, Chanakya Nath
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438340/
https://ncbi.nlm.nih.gov/pubmed/28526868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02134-z
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