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Chemogenetic enhancement of functional recovery after a sciatic nerve injury

Designer receptors exclusively activated by designer drugs (DREADDs) are chemogenetic tools used to modulate neuronal excitability. We hypothesized that activation of excitatory (Gq) DREADD by its designer ligand, clozapine-N-oxide (CNO), would increase the excitability of neurons whose axons have b...

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Neurosci
Hauptverfasser: Jaiswal, Poonam B, English, Arthur W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438293/
https://ncbi.nlm.nih.gov/pubmed/28244163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.13550
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