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Chemogenetic enhancement of functional recovery after a sciatic nerve injury

Designer receptors exclusively activated by designer drugs (DREADDs) are chemogenetic tools used to modulate neuronal excitability. We hypothesized that activation of excitatory (Gq) DREADD by its designer ligand, clozapine-N-oxide (CNO), would increase the excitability of neurons whose axons have b...

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Detalhes bibliográficos
Publicado no:Eur J Neurosci
Main Authors: Jaiswal, Poonam B, English, Arthur W
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438293/
https://ncbi.nlm.nih.gov/pubmed/28244163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.13550
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