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5-Hydroxytryptophan, a precursor for serotonin synthesis, reduces seizure-induced respiratory arrest
OBJECTIVE: The DBA/1 mouse is a relevant animal model of sudden unexpected death in epilepsy (SUDEP), as it exhibits seizure-induced respiratory arrest (S-IRA) evoked by acoustic stimulation, followed by cardiac arrhythmia and death. Defects in serotonergic neurotransmission may contribute to S-IRA....
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| Publicado no: | Epilepsia |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5437865/ https://ncbi.nlm.nih.gov/pubmed/27302625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13430 |
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