Optogenetic Activation of 5-HT Neurons in the Dorsal Raphe Suppresses Seizure-Induced Respiratory Arrest and Produces Anticonvulsant Effect in the DBA/1 Mouse SUDEP Model

Sudden unexpected death in epilepsy (SUDEP) is a devastating epilepsy complication. Seizure-induced respiratory arrest (S-IRA) occurs in many witnessed SUDEP patients and animal models as an initiating event leading to death. Thus, understanding the mechanisms underlying S-IRA will advance the devel...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Zhang, Honghai, Zhao, Haiting, Zeng, Chang, Van Dort, Christa, Faingold, Carl L., Taylor, Norman E., Solt, Ken, Feng, Hua-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748009/
https://ncbi.nlm.nih.gov/pubmed/29141182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.11.003
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