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Inhibition of the Serotonin Transporter Is Altered by Metabolites of Selective Serotonin and Norepinephrine Reuptake Inhibitors and Represents a Caution to Acute or Chronic Treatment Paradigms
[Image: see text] Previous studies of transgenic mice carrying a single isoleucine to methionine substitution (I172M) in the serotonin transporter (SERT) demonstrated a loss of sensitivity to multiple antidepressants (ADs) at SERT. However, the ability of AD metabolites to antagonize SERT was not as...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | ACS Chem Neurosci |
|---|---|
| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Chemical
Society
2016
|
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5437659/ https://ncbi.nlm.nih.gov/pubmed/27959497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.6b00343 |
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