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Analysis of the DNA methylation level of cancer-related genes in colorectal cancer and the surrounding normal mucosa

BACKGROUND: Two molecular pathways promote the development of colorectal cancer (CRC). One is termed “microsatellite stable” (MSS) whereas the other is characterized by “microsatellite instability” (MSI or MIN). In addition, the CpG island methylation phenotype is known to be an important alteration...

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Publicat a:Clin Epigenetics
Autors principals: Sugai, Tamotsu, Yoshida, Masakazu, Eizuka, Makoto, Uesugii, Noriyuki, Habano, Wataru, Otsuka, Kouki, Sasaki, Akira, Yamamoto, Eiichiro, Matsumoto, Takayuki, Suzuki, Hiromu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437595/
https://ncbi.nlm.nih.gov/pubmed/28533824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0352-4
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