Molecular alterations in colorectal adenomas and intramucosal adenocarcinomas defined by high-density single-nucleotide polymorphism arrays

BACKGROUND: We examined colorectal adenomas and intramucosal adenocarcinomas (IMAs) to develop a genome-wide overview of copy number alterations (CNAs) during colorectal tumorigenesis. METHODS: We analysed CNAs using a high-resolution SNP array of isolated tumour glands obtained from 55 colorectal a...

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Veröffentlicht in:J Gastroenterol
Hauptverfasser: Eizuka, Makoto, Sugai, Tamotsu, Habano, Wataru, Uesugi, Noriyuki, Takahashi, Yayoi, Kawasaki, Keisuke, Yamamoto, Eiichiro, Suzuki, Hiromu, Matsumoto, Takayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Japan 2017
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Original Article—Alimentary Tract
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666076/
https://ncbi.nlm.nih.gov/pubmed/28197804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00535-017-1317-2
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