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Highly specific imaging of mRNA in single cells by target RNA-initiated rolling circle amplification
Detection of single-cell gene expression with high spatial and sequence resolution is a key challenge in single cell biology. Herein, we propose a robust method for the direct detection of mRNA, termed target RNA-initiated rolling circle amplification, which enables imaging of mRNA with single-nucle...
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| Publicat a: | Chem Sci |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Royal Society of Chemistry
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5437493/ https://ncbi.nlm.nih.gov/pubmed/28580104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc00292k |
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