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Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells
Metastases are the leading cause of mortality in patients with cancer. Metastasis formation requires cancer cells to adapt their cellular phenotype. However, how metabolism supports this adaptation of cancer cells is poorly defined. We use 2D versus 3D cultivation to induce a shift in the cellular p...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5437289/ https://ncbi.nlm.nih.gov/pubmed/28492237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15267 |
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