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An antidote approach to reduce risk and broaden utility of antibody-based therapeutics

Antibody therapeutics offer effective treatment options for a broad range of diseases. One of the greatest benefits of antibody therapeutics is their extraordinarily long serum half-life, allowing infrequent dosing with long-lasting effects. A characteristic of antibodies that drives long half-life...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Portnoff, Alyse D., Gao, Cuihua, Borrok, M. Jack, Gao, Xizhe, Gao, Changshou, Rainey, G. Jonah
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437253/
https://ncbi.nlm.nih.gov/pubmed/28258216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.775528
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