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The antihelminthic drug niclosamide effectively inhibits the malignant phenotypes of uveal melanoma in vitro and in vivo

Uveal melanoma (UM) is a lethal intraocular malignancy with an average survival of only 2~8 months in patients with hepatic metastasis. Currently, there is no effective therapy for metastatic UM. Here, we reported that niclosamide, an effective repellence of tapeworm that has been approved for use i...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Zhou, Jingfeng, Jin, Bei, Jin, Yanli, Liu, Yizhi, Pan, Jingxuan
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436505/
https://ncbi.nlm.nih.gov/pubmed/28529629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.17451
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