Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia

Natural killer (NK) cells are an emerging cellular immunotherapy for patients with acute myeloid leukemia (AML); however, the best approach to maximize NK cell antileukemia potential is unclear. Cytokine-induced memory-like NK cells differentiate after a brief preactivation with interleukin-12 (IL-1...

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Gepubliceerd in:Sci Transl Med
Hoofdauteurs: Romee, Rizwan, Rosario, Maximillian, Berrien-Elliott, Melissa M., Wagner, Julia A., Jewell, Brea A., Schappe, Timothy, Leong, Jeffrey W., Abdel-Latif, Sara, Schneider, Stephanie E., Willey, Sarah, Neal, Carly C., Yu, Liyang, Oh, Stephen T., Lee, Yi-Shan, Mulder, Arend, Claas, Frans, Cooper, Megan A., Fehniger, Todd A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436500/
https://ncbi.nlm.nih.gov/pubmed/27655849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf2341
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