Recombinant AAV8-mediated intrastriatal gene delivery of CDNF protects rats against methamphetamine neurotoxicity

Methamphetamine (METH) exerts significant neurotoxicity in experimental animals and humans when taken at high doses or abused chronically. Long-term abusers have decreased dopamine levels, and they are more likely to develop Parkinson's disease (PD). To date, few medications are available to tr...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Wang, Lizheng, Wang, Zixuan, Xu, Xiaoyu, Zhu, Rui, Bi, Jinpeng, Liu, Wenmo, Feng, Xinyao, Wu, Hui, Zhang, Haihong, Wu, Jiaxin, Kong, Wei, Yu, Bin, Yu, Xianghui
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436476/
https://ncbi.nlm.nih.gov/pubmed/28553166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.18623
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