Muscle Contraction Regulates BDNF/TrkB Signaling to Modulate Synaptic Function through Presynaptic cPKCα and cPKCβI

The neurotrophin brain-derived neurotrophic factor (BDNF) acts via tropomyosin-related kinase B receptor (TrkB) to regulate synapse maintenance and function in the neuromuscular system. The potentiation of acetylcholine (ACh) release by BDNF requires TrkB phosphorylation and Protein Kinase C (PKC) a...

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Publicat a:Front Mol Neurosci
Autors principals: Hurtado, Erica, Cilleros, Víctor, Nadal, Laura, Simó, Anna, Obis, Teresa, Garcia, Neus, Santafé, Manel M., Tomàs, Marta, Halievski, Katherine, Jordan, Cynthia L., Lanuza, Maria A., Tomàs, Josep
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436293/
https://ncbi.nlm.nih.gov/pubmed/28572757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00147
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