Presynaptic muscarinic acetylcholine autoreceptors (M(1), M(2) and M(4) subtypes), adenosine receptors (A(1) and A(2A)) and tropomyosin-related kinase B receptor (TrkB) modulate the developmental synapse elimination process at the neuromuscular junction

BACKGROUND: The development of the nervous system involves an initially exuberant production of neurons that make an excessive number of synaptic contacts. The initial overproduction of synapses promotes connectivity. Hebbian competition between axons with different activities (the least active are...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Nadal, Laura, Garcia, Neus, Hurtado, Erica, Simó, Anna, Tomàs, Marta, Lanuza, Maria A., Santafé, Manel, Tomàs, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917939/
https://ncbi.nlm.nih.gov/pubmed/27339059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0248-9
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