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Role of the Wnt/β-catenin signaling pathway in inducing apoptosis and renal fibrosis in 5/6-nephrectomized rats

Renal fibrosis is the final common pathway of all progressive renal disease. Excessive and chronic activation of the Wnt/β-catenin signaling pathway results in chronic kidney disease (CKD) progression. To mimic CKD, the present study used 5/6-nephrectomized rats, and alterations in kidney histology,...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Lin, Xin, Zha, Yan, Zeng, Xiang-Zhen, Dong, Rong, Wang, Qing-Hua, Wang, Dong-Tao
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436235/
https://ncbi.nlm.nih.gov/pubmed/28440442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6461
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