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Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice
PHF8 is a histone demethylase with specificity for repressive modifications. While mutations of PHF8 have been associated with cognitive defects and cleft lip/palate, its role in mammalian development and physiology remains unexplored. Here, we have generated a Phf8 knockout allele in mice to examin...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5436068/ https://ncbi.nlm.nih.gov/pubmed/28485378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15142 |
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