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Nucleic acid detection using BRET-beacons based on bioluminescent protein–DNA hybrids
Bioluminescent molecular beacons have been developed using a modular design approach that relies on BRET between the bright luciferase NanoLuc and a Cy3 acceptor. While classical molecular beacons are hampered by background fluorescence and scattering, these BRET-beacons allow detection of low pM co...
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| 發表在: | Chem Commun (Camb) |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Royal Society of Chemistry
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5436041/ https://ncbi.nlm.nih.gov/pubmed/28217801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc10032e |
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