Enzymatic Amplification of DNA/RNA Hybrid Molecular Beacon Signaling in Nucleic Acid Detection

A rapid assay operable under isothermal or non-isothermal conditions is described wherein the sensitivity of a typical molecular beacon (MB) system is improved by utilizing thermostable RNase H to enzymatically cleave an MB comprised of a DNA stem and RNA loop (R/D-MB). Upon hybridization of the R/D...

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Bibliographic Details
Main Authors:	Jacroux, Thomas, Rieck, Daniel C., Cui, Rong, Ouyang, Yexin, Dong, Wen-Ji
Format:	Artigo
Language:	Inglês
Published:	2012
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3522425/ https://ncbi.nlm.nih.gov/pubmed/23000602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.09.015
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Enzymatic Amplification of DNA/RNA Hybrid Molecular Beacon Signaling in Nucleic Acid Detection

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