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Dissection of ubiquitinated protein degradation by basal autophagy

Basal autophagy plays an essential role as a protein quality control system. Although it has been demonstrated that the loss of autophagy results in the accumulation of ubiquitin‐positive aggregates and the development of neurodegenerative diseases, the precise autophagy substrate(s) remain unclear....

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Takayama, Kaori, Matsuura, Akira, Itakura, Eisuke
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435929/
https://ncbi.nlm.nih.gov/pubmed/28369861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12641
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