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Microprocessor dynamics shows co- and post-transcriptional processing of pri-miRNAs

miRNAs are small regulatory RNAs involved in the regulation of translation of target transcripts. miRNA biogenesis is a multistep process starting with the cleavage of the primary miRNA transcript in the nucleus by the Microprocessor complex. Endogenous processing of pri-miRNAs is challenging to stu...

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Bibliografiske detaljer
Udgivet i:RNA
Main Authors: Louloupi, Annita, Ntini, Evgenia, Liz, Julia, Ørom, Ulf Andersson
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435862/
https://ncbi.nlm.nih.gov/pubmed/28250203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.060715.117
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