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Single-cell transcriptomics reveals specific RNA editing signatures in the human brain

While RNA editing by A-to-I deamination is a requisite for neuronal function in humans, it is under-investigated in single cells. Here we fill this gap by analyzing RNA editing profiles of single cells from the brain cortex of living human subjects. We show that RNA editing levels per cell are bimod...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Picardi, Ernesto, Horner, David S., Pesole, Graziano
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435858/
https://ncbi.nlm.nih.gov/pubmed/28258159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.058271.116
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