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Single-cell transcriptomics reveals specific RNA editing signatures in the human brain

While RNA editing by A-to-I deamination is a requisite for neuronal function in humans, it is under-investigated in single cells. Here we fill this gap by analyzing RNA editing profiles of single cells from the brain cortex of living human subjects. We show that RNA editing levels per cell are bimod...

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Bibliografske podrobnosti
izdano v:RNA
Main Authors: Picardi, Ernesto, Horner, David S., Pesole, Graziano
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435858/
https://ncbi.nlm.nih.gov/pubmed/28258159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.058271.116
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