Persistence of Innate Immune Pathways in Late Stage Human Bacterial and Fungal Keratitis: Results from a Comparative Transcriptome Analysis

Microbial keratitis (MK) is a major cause of blindness worldwide. Despite adequate antimicrobial treatment, tissue damage can ensue. We compared the human corneal transcriptional profile in late stage MK to normal corneal tissue to identify pathways involved in pathogenesis. Total RNA from MK tissue...

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Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: Chidambaram, Jaya D., Kannambath, Shichina, Srikanthi, Palepu, Shah, Manisha, Lalitha, Prajna, Elakkiya, Shanmugam, Bauer, Julien, Prajna, Namperumalsamy V., Holland, Martin J., Burton, Matthew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435826/
https://ncbi.nlm.nih.gov/pubmed/28573109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00193
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