Persistence of Innate Immune Pathways in Late Stage Human Bacterial and Fungal Keratitis: Results from a Comparative Transcriptome Analysis

Microbial keratitis (MK) is a major cause of blindness worldwide. Despite adequate antimicrobial treatment, tissue damage can ensue. We compared the human corneal transcriptional profile in late stage MK to normal corneal tissue to identify pathways involved in pathogenesis. Total RNA from MK tissue...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Chidambaram, Jaya D., Kannambath, Shichina, Srikanthi, Palepu, Shah, Manisha, Lalitha, Prajna, Elakkiya, Shanmugam, Bauer, Julien, Prajna, Namperumalsamy V., Holland, Martin J., Burton, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435826/
https://ncbi.nlm.nih.gov/pubmed/28573109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00193
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