Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancer

Y-box binding protein 1 (YB-1) is an RNA and DNA binding factor with potential prognostic cancer. To evaluate the clinical impact of YB-1, a tissue microarray with 11,152 prostate cancers was analysed by immunohistochemistry. Cytoplasmic and nuclear staining was separately analysed. Cytoplasmic YB-1...

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Publicat a:Sci Rep
Autors principals: Heumann, Asmus, Kaya, Özge, Burdelski, Christoph, Hube-Magg, Claudia, Kluth, Martina, Lang, Dagmar S., Simon, Ronald, Beyer, Burkhard, Thederan, Imke, Sauter, Guido, Izbicki, Jakob R., Luebke, Andreas M., Hinsch, Andrea, Jacobsen, Frank, Wittmer, Corinna, Büscheck, Franziska, Höflmayer, Doris, Minner, Sarah, Tsourlakis, Maria Christina, Schlomm, Thorsten, Wilczak, Waldemar
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435682/
https://ncbi.nlm.nih.gov/pubmed/28515422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02279-x
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