Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancer

Y-box binding protein 1 (YB-1) is an RNA and DNA binding factor with potential prognostic cancer. To evaluate the clinical impact of YB-1, a tissue microarray with 11,152 prostate cancers was analysed by immunohistochemistry. Cytoplasmic and nuclear staining was separately analysed. Cytoplasmic YB-1...

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Publicado en:Sci Rep
Autores principales: Heumann, Asmus, Kaya, Özge, Burdelski, Christoph, Hube-Magg, Claudia, Kluth, Martina, Lang, Dagmar S., Simon, Ronald, Beyer, Burkhard, Thederan, Imke, Sauter, Guido, Izbicki, Jakob R., Luebke, Andreas M., Hinsch, Andrea, Jacobsen, Frank, Wittmer, Corinna, Büscheck, Franziska, Höflmayer, Doris, Minner, Sarah, Tsourlakis, Maria Christina, Schlomm, Thorsten, Wilczak, Waldemar
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435682/
https://ncbi.nlm.nih.gov/pubmed/28515422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02279-x
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