Mutation Analysis of the Histidine Residues in the Glycylglycine Endopeptidase ALE-1

A novel staphylolytic enzyme, ALE-1, is a glycylglycine endopeptidase produced by Staphylococcus capitis EPK1. ALE-1 possesses seven histidines. Chemical modification studies using diethylpyrocarbonate and iodoacetic acid suggested that a histidine or tyrosine residue(s) in the molecule is important...

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Detalhes bibliográficos
Main Authors: Fujiwara, Tamaki, Aoki, Shin, Komatsuzawa, Hitoshi, Nishida, Tetsuya, Ohara, Masaru, Suginaka, Hidekazu, Sugai, Motoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Enzymes and Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC543547/
https://ncbi.nlm.nih.gov/pubmed/15629919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.2.480-487.2005
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