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Rapid evolution of the human mutation spectrum

DNA is a remarkably precise medium for copying and storing biological information. This high fidelity results from the action of hundreds of genes involved in replication, proofreading, and damage repair. Evolutionary theory suggests that in such a system, selection has limited ability to remove gen...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Harris, Kelley, Pritchard, Jonathan K
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435464/
https://ncbi.nlm.nih.gov/pubmed/28440220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24284
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