Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment

Antibiotic resistance arising via chromosomal mutations is typically specific to a particular antibiotic or class of antibiotics. We have identified mutations in genes encoding ribosomal components in Mycobacterium smegmatis that confer resistance to several structurally and mechanistically unrelate...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Gomez, James E, Kaufmann-Malaga, Benjamin B, Wivagg, Carl N, Kim, Peter B, Silvis, Melanie R, Renedo, Nikolai, Ioerger, Thomas R, Ahmad, Rushdy, Livny, Jonathan, Fishbein, Skye, Sacchettini, James C, Carr, Steven A, Hung, Deborah T
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Genomics and Evolutionary Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319836/
https://ncbi.nlm.nih.gov/pubmed/28220755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20420
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