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Multidrug-Resistant Tuberculosis in Panama Is Driven by Clonal Expansion of a Multidrug-Resistant Mycobacterium tuberculosis Strain Related to the KZN Extensively Drug-Resistant M. tuberculosis Strain from South Africa

Multidrug-resistant tuberculosis (MDR-TB) is a significant health problem in Panama. The extent to which such cases are the result of primary or acquired resistance and the strain families involved are unknown. We performed whole-genome sequencing of a collection of 66 clinical MDR isolates, along w...

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Detalhes bibliográficos
Main Authors: Lanzas, Fedora, Karakousis, Petros C., Sacchettini, James C., Ioerger, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811646/
https://ncbi.nlm.nih.gov/pubmed/23884993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01122-13
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