MHC Ib molecule Qa-1 presents Mycobacterium tuberculosis peptide antigens to CD8(+) T cells and contributes to protection against infection

A number of nonclassical MHC Ib molecules recognizing distinct microbial antigens have been implicated in the immune response to Mycobacterium tuberculosis (Mtb). HLA-E has been identified to present numerous Mtb peptides to CD8(+) T cells, with multiple HLA-E-restricted cytotoxic T lymphocyte (CTL)...

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Publicat a:PLoS Pathog
Autors principals: Bian, Yao, Shang, Shaobin, Siddiqui, Sarah, Zhao, Jie, Joosten, Simone A., Ottenhoff, Tom H. M., Cantor, Harvey, Wang, Chyung-Ru
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435364/
https://ncbi.nlm.nih.gov/pubmed/28475642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006384
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